Redfield meets his new partner Sheva Alomar

The title takes place five years after the events of Resident Evil 4 and eleven years after the Raccoon City events of 1998. This chapter, set in 2009, marks the return of Chris Redfield, former agent of S.T.A.R.S. part time organization BSAA committed to destroy all biological weapons (B.O.W) in circulation. Chris is sent to Africa where it will be an exchange of biological weapons. Arrived in the village of Kijuju, Redfield meets his new partner Sheva Alomar, and began to search for clues to uncover the truth about a new virus called Uroboros. In this game still appears Albert Wesker, as the main enemy Cosplay UK
. In the final uses of the Uroboros virus to become a monster; However, Chris and Sheva defeat him making him sink into the lava and escaping by helicopter. Wesker will attempt to stop them but with a double shot of rocket launchers Sheva and Chris will kill him beheading and causing it to explode.

This chapter takes place between late 2012 and 2013. The protagonists are Leon S. Kennedy and Chris Redfield, the main representatives of the series, Jake Muller and son of Albert Wesker. Each of them is supported by a "shoulder", respectively Helena Harper, Piers Nivans and Sherry Birkin, the latter is the little girl rescued by Claire during the Raccoon City tragedy, grown and become an agent of the government. The game speaks bioterrorist attack implemented by Neo-Umbrella, a pharmaceutical company bioterrorism that with the help of Derek C. Simmons has created a new pathogen called C-virus with which it has spread an epidemic on a large scale in the city of Tall Oaks, Edonia and China Metal Gear Solid Cosplay
. The effects of this virus are varied however according to how it is contracted the virus C infection, you have different effects: the virus can be transformed into zombies, if inhaled, or if J'avo is inoculated. The J'avo have infected humans C virus intelligent and changeling, while the zombies are similar to those created by the T-virus, with the difference that present changes that make them more dangerous and resistant. It will be up to Leon, Chris and Jake flanked by their respective partners, foiling the bioterrorist attacks at the hands of the Neo-Umbrella and Simmons, and find the key to defeating the new dangerous C virus that threatens the existence of mankind. Jake, in fact, is the only one to have antibodies that make it immune to the virus C and could lead to a vaccine with his blood.